The impact of glucosamine on age-related macular degeneration in patients: A nationwide, population-based cohort study.

ABSTRACT:

Purpose

To analyze the association between glucosamine (GlcN) use and the risk of age-related macular degeneration (AMD) using claims data from the National Health Insurance Research Database (NHIRD).

Methods

A retrospective, population-based study was conducted with NHIRD data from a 14-year period (2000-2013). Chi-squared and Student's t-tests were used to evaluate differences between the study and comparison cohorts for categorical and continuous variables, respectively. Risk factors for disease development were examined by the adjusted hazard ratio (aHR) with 95% confidence interval. Kaplan-Meier analysis was performed to compare the cumulative risk of AMD between the two cohorts.

Results

In total, 1,344 patients with GlcN treatment were enrolled in the study coho

SUBMITTER: Feng KM 

PROVIDER: S-EPMC8133402 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature