Association of gray matter volumes with general and specific dimensions of psychopathology in children.

ABSTRACT: Childhood is an important time for the manifestation of psychopathology. Psychopathology is characterized by considerable comorbidity which is mirrored in the underlying neural correlates of psychopathology. Both common and dissociable variations in brain volume have been found across multiple mental disorders in adult and youth samples. However, the majority of these studies used samples with broad age ranges which may obscure developmental differences. The current study examines associations between regional gray matter volumes (GMV) and psychopathology in a large sample of children with a narrowly defined age range. We used data from 9607 children 9-10 years of age collected as part of the Adolescent Brain Cognitive Development^SM Study (ABCD Study^®). A bifactor mod

SUBMITTER: Durham EL 

PROVIDER: S-EPMC8134562 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature