Characterization of microRNAs from neem (Azadirachta indica) and their tissue-specific expression study in leaves and stem.

ABSTRACT: Neem (Azadirachta indica) is a very popular traditional medicinal plant used since ancient times to treat numerous ailments. MicroRNAs (miRNAs) are highly conserved, non-coding, short RNA molecules that play important regulatory roles in plant development and metabolism. In this study, deploying a high stringent genome-wide computational-based approach and following a set of strict filtering norms a total of 44 potential conserved neem miRNAs belonging to 21 families and their corresponding 48 potential target transcripts were identified. Important targets include Squamosa promoter binding protein-like proteins, NAC, Scarecrow proteins, Auxin response factor, and F-box proteins. A biological network has also been developed to understand the miRNA-mediated gene regulation using the m

SUBMITTER: Paul S 

PROVIDER: S-EPMC8134612 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature