Clinicopathological Characteristics and Surgical Outcomes of Crohn Disease-Associated Colorectal Malignancy.

ABSTRACT:

Purpose

Carcinoma arising from Crohn disease (CD) is rare, and there is no clear guidance on how to properly screen for at-risk patients and choose appropriate care. This study aimed to evaluate the clinicopathological characteristics, treatment, and oncologic outcomes of CD patients diagnosed with colorectal cancer (CRC).

Methods

Using medical records, we retrospectively enrolled a single-center cohort of 823 patients who underwent abdominal surgery for CD between January 2006 and December 2015. CD-associated CRC patients included those with adenocarcinoma, lymphoma, or neuroendocrine tumors of the colon and rectum.

Results

Nineteen patients (2.3%) underwent abdominal surgery to treat CD-associated CRC. The mean duration of CD in the CD-associated CRC group was signi

SUBMITTER: Lee YN 

PROVIDER: S-EPMC8134931 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature