Does treatment sequence affect outcomes in patients with metaplastic breast cancer?

ABSTRACT:

Introduction

We compared characteristics and outcomes by treatment sequence among patients with metaplastic breast cancer (MBC), an aggressive subtype.

Methods

Women ≥18 years old with newly diagnosed Stage I-III MBC from 2003 to 2018 who received any treatment in our health system were identified. Unadjusted overall survival (OS) was estimated with the Kaplan-Meier method; the log-rank test was used to compare survival differences between recipients of neoadjuvant (NACT) and adjuvant chemotherapy (ACT).

Results

Of the 91 MBC patients identified, 60 received chemotherapy. NACT recipients (n = 20, median age 46.5 y) were younger than ACT recipients (n = 40, median age 60.5 y, p < 0.001) but similar with regards to race and radiation receipt. There was no significant OS

SUBMITTER: Ladipo OL 

PROVIDER: S-EPMC8134971 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature