Resting State Connectivity Is Modulated by Motor Learning in Individuals After Stroke.

ABSTRACT:

Objective

Activity patterns across brain regions that can be characterized at rest (ie, resting-state functional connectivity [rsFC]) are disrupted after stroke and linked to impairments in motor function. While changes in rsFC are associated with motor recovery, it is not clear how rsFC is modulated by skilled motor practice used to promote recovery. The current study examined how rsFC is modulated by skilled motor practice after stroke and how changes in rsFC are linked to motor learning.

Methods

Two groups of participants (individuals with stroke and age-matched controls) engaged in 4 weeks of skilled motor practice of a complex, gamified reaching task. Clinical assessments of motor function and impairment, and brain activity (via functional magnetic resonance imaging) we

SUBMITTER: Kraeutner SN 

PROVIDER: S-EPMC8135242 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature