A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal.
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ABSTRACT:
SUBMITTER: Cordes Selby S
PROVIDER: S-EPMC8136447 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
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A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal.
Cordes Selby Susan S Iwata-Otsubo Aiko A Delk Paula P Nebesio Todd D TD Gohil Anisha A Matlock Peggy P Torres-Martinez Wilfredo W Vance Gail H GH
Clinical case reports 20210506 5
Two siblings with the same male unbalanced karyotype demonstrate sex reversal. The older sib appeared phenotypically female and the younger sib demonstrated a male gender. The female had gonadal dysgenesis with bilateral ovatestes. The male had bilateral testes. The report discusses the phenotypical differences and genes associated with sex reversal. ...[more]
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