Corticosteroid therapy for COVID-19: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Corticosteroid treatment is an effective and common therapeutic strategy for various inflammatory lung pathologies and may be an effective treatment for coronavirus disease 2019 (COVID-19). The purpose of this systematic review and meta-analysis of current literature was to investigate the clinical outcomes associated with corticosteroid treatment of COVID-19.

Methods

We systematically searched PubMed, medRxiv, Web of Science, and Scopus databases through March 10, 2021 to identify randomized controlled trials (RCTs) that evaluated the effects of corticosteroid therapies for COVID-19 treatment. Outcomes of interest were mortality, need for mechanical ventilation, serious adverse events (SAEs), and superinfection.

Results

A total of 7737 patients from 8 RCTs

SUBMITTER: Pulakurthi YS 

PROVIDER: S-EPMC8137023 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature