Clinical impact of long-term change in air trapping on pulmonary function and computed tomography parameters in chronic obstructive pulmonary disease.

ABSTRACT:

Background/aims

Air trapping is associated with unfavorable outcomes in chronic obstructive pulmonary disease (COPD). The present study evaluated the association between longitudinal changes in air trapping with pulmonary function, computed tomography (CT) parameters and exacerbation.

Methods

Patients enrolled in the Korean Obstructive Lung Disease (KOLD) study cohort from June 2005 to October 2015 were included. The study patients were categorized into four groups according to the change in residual volume to total lung capacity ratio (RV/TLC) over 3 years. The RV/TLC was considered abnormal when it was ≥ 40% and normal when it was < 40%.

Results

A total of 279 patients were categorized into four groups: 76 in the "normal to normal" (N→N) group, 34 in the "abnormal t

SUBMITTER: Lim JU 

PROVIDER: S-EPMC8137389 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature