Predicting survival after liver transplantation in patients with hepatocellular carcinoma using the LiTES-HCC score.

ABSTRACT:

Background & aims

Liver transplant priority in the US and Europe follows the 'sickest-first' principle. However, for patients with hepatocellular carcinoma (HCC), priority is based on binary tumor criteria to expedite transplant for patients with 'acceptable' post-transplant outcomes. Newer risk scores developed to overcome limitations of these binary criteria are insufficient to be used for waitlist priority as they focus solely on HCC-related pre-transplant variables. We sought to develop a risk score to predict post-transplant survival for patients using HCC- and non-HCC-related variables.

Methods

We performed a retrospective cohort study using national registry data on adult deceased-donor liver transplant (DDLT) recipients with HCC from 2/27/02-12/31/18. We fit Cox regr

SUBMITTER: Goldberg D 

PROVIDER: S-EPMC8137533 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature