Periodontal manifestations of Langerhans cell histiocytosis: a systematic review.

ABSTRACT:

Objectives

To explore the evidence of periodontal manifestations and treatment modalities in patients with Langerhans cell histiocytosis (LCH).

Material and methods

A systematic literature search was performed and the criteria for PRISMA and risk of bias assessment were applied. Human clinical studies (≥10 patients) presenting patients with LCH and periodontal findings were considered for inclusion.

Results

From 298 titles identified, six case series with a total of 1278 patients suffering from LCH were included. In these studies, oral symptoms were reported in a frequency ranging from 10 to 100%. Overall, in 216 patients (17%), oral symptoms were observed. Out of these patients, 49-100% demonstrated periodontal symptoms. The most common oral findings were pain, swell

SUBMITTER: Difloe-Geisert JC 

PROVIDER: S-EPMC8137606 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature