Craving mediates the association between momentary pain and illicit opioid use during treatment for opioid-use disorder: an ecological momentary assessment study.

ABSTRACT:

Aim

To assess the role of momentary pain on opioid craving and illicit opioid use among individuals receiving opioid agonist treatment.

Design

Observational study using ecological momentary assessment.

Setting

The National Institute of Drug Abuse Intramural Research Program in the United States.

Participants

Fifty-six adults who qualified for opioid agonist treatment.

Measurements

Participants completed randomly prompted assessments of pain severity, stress, negative mood, opioid craving and illicit opioid use for a mean of 66 days [standard deviation (SD) = 27]. Urine samples were collected two to three times/week throughout.

Findings

Almost 70% of participants reported moderate average pain severity in the past 24 hours at intake and 35% of part

SUBMITTER: Mun CJ 

PROVIDER: S-EPMC8137724 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature