Ontology highlight
ABSTRACT:
SUBMITTER: Mei W
PROVIDER: S-EPMC8138819 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Mei Wenwen W Jiang Zhiwen Z Chen Yang Y Chen Li L Sancar Aziz A Jiang Yuchao Y
Briefings in bioinformatics 20210501 3
Circadian rhythms are oscillations of behavior, physiology and metabolism in many organisms. Recent advancements in omics technology make it possible for genome-wide profiling of circadian rhythms. Here, we conducted a comprehensive analysis of seven existing algorithms commonly used for circadian rhythm detection. Using gold-standard circadian and non-circadian genes, we systematically evaluated the accuracy and reproducibility of the algorithms on empirical datasets generated from various omic ...[more]