More Severe COVID-19 in Patients With Active Cancer: Results of a Multicenter Cohort Study.

ABSTRACT:

Background

The aim of the study was to compare coronavirus disease 2019 (COVID-19) severity presentation between oncologic and non-oncologic patients and to evaluate the impact of cancer type and stage on COVID-19 course.

Methods

We performed a multicentre, retrospective study involving 13 COVID-19 Units in Campania region from February to May 2020. We defined as severe COVID-19 presentation the cases that required mechanical ventilation and/or admission to Intensive Care Units (ICU) and/or in case of death.

Results

We enrolled 371 COVID-19 patients, of whom 34 (9.2%) had a history or a diagnosis of cancer (24 solid, 6 onco-hematological). Oncologic patients were older (p<0.001), had more comorbidities (p<0.001) and showed a higher rate of severe COVID-19 presentation

SUBMITTER: Monari C 

PROVIDER: S-EPMC8139554 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature