One Versus Up-to-5 Lesion Measurements for Response Assessment by PERCIST in Patients with Lung Cancer.

ABSTRACT:

Purpose

The optimal number of lesions to measure for response assessment from fluorine-18 fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET)/computed tomography (CT) is not validated for lung cancer. We compared 1 lesion and up-to-5 lesion measurements for response assessment in lung cancer per PET Response Criteria in Solid Tumors (PERCIST).

Methods

Patients with lung cancer with pre- and post-treatment PET/CT images were included. The standard uptake value corrected for lean body mass (SUL_peak) of up-to-5 hottest target lesions was measured at each time point. The percent changes of SUL_peak of the single hottest lesion and the sum of up-to-5 hottest lesions were computed. Pearson correlation coefficient evaluated the strength o

SUBMITTER: Kwon SJ 

PROVIDER: S-EPMC8140042 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature