Ten-year attrition and antiretroviral therapy response among HIV-positive adults: a sex-based cohort analysis from eight West African countries.

ABSTRACT:

Introduction

Sex differences have already been reported in sub-Saharan Africa for attrition and immunological response after antiretroviral therapy (ART) initiation, but follow-up was usually limited to the first two to three years after ART initiation. We evaluated sex differences on the same outcomes in the 10 years following ART initiation in West African adults.

Methods

We used cohort data of patients included in the IeDEA West Africa collaboration, who initiated ART between 2002 and 2014. We modelled no-follow-up and 10-year attrition risks, and immunological response by sex using logistic regression analysis, survival analysis with random effect and linear mixed models respectively.

Results

A total of 71,283 patients (65.8% women) contributed to 310,007 person-y

SUBMITTER: Tiendrebeogo T 

PROVIDER: S-EPMC8140184 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature