Age-specific cut-off levels of anti-Mullerian hormone can be used as diagnostic markers for polycystic ovary syndrome.

ABSTRACT:

Background

The majority of available studies on the AMH thresholds were not age-specific and performed the receiver operating characteristic curve (ROC) analysis, based on variations in sensitivity and specificity rather than positive and negative predictive values (PPV and NPV, respectively), which are more clinically applicable. Moreover, all of these studies used a pre-specified age categorization to report the age-specific cut-off values of AMH.

Methods

A total of 803 women, including 303 PCOS patients and 500 eumenorrheic non-hirsute control women, were enrolled in the present study. The PCOS group included PCOS women, aged 20-40 years, who were referred to the Reproductive Endocrinology Research Center, Tehran, Iran. The Rotterdam consensus criteria were used for diagn

SUBMITTER: Ramezani Tehrani F 

PROVIDER: S-EPMC8140506 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature