Comparative evaluation of six nucleic acid amplification kits for SARS-CoV-2 RNA detection.

ABSTRACT:

Background

SARS-CoV-2 is a newly emerged coronavirus, causing the coronavirus disease 2019 (COVID-19) outbreak in December, 2019. As drugs and vaccines of COVID-19 remain in development, accurate virus detection plays a crucial role in the current public health crisis. Quantitative real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) kits have been reliably used for detection of SARS-CoV-2 RNA since the beginning of the COVID-19 outbreak, whereas isothermal nucleic acid amplification-based point-of-care automated kits have also been considered as a simpler and rapid alternative. However, as these kits have only been developed and applied clinically within a short timeframe, their clinical performance has not been adequately evaluated to date. We describe a comparativ

SUBMITTER: Wu S 

PROVIDER: S-EPMC8140580 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature