Identifying degenerative effects of repetitive head trauma with neuroimaging: a clinically-oriented review.

ABSTRACT:

Background and scope of review

Varying severities and frequencies of head trauma may result in dynamic acute and chronic pathophysiologic responses in the brain. Heightened attention to long-term effects of head trauma, particularly repetitive head trauma, has sparked recent efforts to identify neuroimaging biomarkers of underlying disease processes. Imaging modalities like structural magnetic resonance imaging (MRI) and positron emission tomography (PET) are the most clinically applicable given their use in neurodegenerative disease diagnosis and differentiation. In recent years, researchers have targeted repetitive head trauma cohorts in hopes of identifying in vivo biomarkers for underlying biologic changes that might ultimately improve diagnosis of chronic traumatic encephalopa

SUBMITTER: Asken BM 

PROVIDER: S-EPMC8141132 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature