Chronic hepatitis D associated with worse patient-reported outcomes than chronic hepatitis B.

ABSTRACT:

Background & aims

Health-related quality of life (HRQoL) determined by patient-reported outcomes (PROs) is impaired in chronic hepatitis B (CHB) and C patients, but there are no data regarding patients with chronic hepatitis D (CHD). The aim of this study was to assess PRO scores in untreated patients with CHD and compare them with those obtained for patients with CHB.

Methods

Patients with CHD completed 3 PRO instruments (Chronic Liver Disease Questionnaire [CLDQ], Functional Assessment of Chronic Illness Therapy-Fatigue [FACIT-F], and Work Productivity and Activity Impairment [WPAI]), and the results were compared with those of patients mono-infected with CHB.

Results

In total, 125 patients were included: 43 with CHD and 82 with CHB. Overall, baseline PROs showed di

SUBMITTER: Buti M 

PROVIDER: S-EPMC8141931 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature