Treatment expectations as a possible prognostic factor for DMARD response in rheumatoid arthritis: a prospective cohort study.

ABSTRACT:

Background

The prediction of the individual's response to disease modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) is challenging and often limited. Here we evaluated the influence of patients' expectations towards a change in treatment with DMARD on clinical outcome in RA.

Methods

One hundred patients (74 female) with RA (2010 ACR/EULAR classification criteria) and an upcoming change in DMARD treatment due to non-response or adverse effects were included. Patients' treatment beliefs, health-related quality of life and treatment expectations were measured using the Beliefs about Medicines Questionnaire (BMQ), the Short Form 36, and self-designed questions about expectations before treatment initiation (T0), and DAS28-CRP was calculated at T0 and after 4 mo

SUBMITTER: Mucke J 

PROVIDER: S-EPMC8142018 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature