Epidemiology and genetic diversity of SARS-CoV-2 lineages circulating in Africa.

ABSTRACT: COVID-19 disease dynamics have been widely studied in different settings around the globe, but little is known about these patterns in the African continent. To investigate the epidemiology and genetic diversity of SARS-CoV-2 lineages circulating in Africa, more than 2400 complete genomes from 33 African countries were retrieved from the GISAID database and analyzed. We investigated their diversity using various clade and lineage nomenclature systems, reconstructed their evolutionary divergence and history using maximum likelihood inference methods, and studied the case and death trends in the continent. We also examined potential repeat patterns and motifs across the sequences. In this study, we show that after almost one year of the COVID-19 pandemic, only 143 out of the 782 Pango lineag

SUBMITTER: Okoh OS 

PROVIDER: S-EPMC8142660 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature