Clinical outcomes in COVID-19 patients infected with different SARS-CoV-2 variants in Marseille, France.

ABSTRACT:

Objectives

To compare the clinical and epidemiological aspects associated with different predominant lineages circulating in Marseille from March 2020 to January 2021.

Methods

In this single-centre retrospective cohort study, characteristics of patients infected with four different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants were documented from medical files. The outcome was the occurrence of clinical failure, defined as hospitalization (for outpatients), transfer to the intensive care unit (inpatients) and death (all).

Results

A total of 254 patients were infected with clade 20A (20AS), 85 with Marseille-1 (M1V), 190 with Marseille-4 (M4V) and 211 with N501Y (N501YV) variants. 20AS presented a bell-shaped epidemiological curve and nearly di

SUBMITTER: Dao TL 

PROVIDER: S-EPMC8142822 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature