Burden and etiology of moderate and severe diarrhea in children less than 5 years of age living in north and south of China: Prospective, population-based surveillance.

ABSTRACT:

Background

Diarrhea remains the leading cause of childhood illness in China. Better understanding of burden and etiology of diarrheal diseases is important for development of effective prevention measures.

Methods

Population-based diarrhea surveillance was conducted in Sanjiang (southern China) year-round and Zhengding (northern China) in autumn/winter. Stool specimens were collected from children < 5 years of age experiencing diarrhea. The TaqMan Array Card (TAC), based on multiplex real-time PCR, was applied to detect multiple enteric microbial agents simultaneously. Results using these methods were compared to those derived from conventional PCR assays.

Results

During the study period, 6,380 children in Zhengding and 3,581 children in Sanjiang < 5 years of age part

SUBMITTER: Zhou HL 

PROVIDER: S-EPMC8142869 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature