Composition of cutaneous bacterial microbiome in seborrheic dermatitis patients: A cross-sectional study.

ABSTRACT:

Background

Seborrheic dermatitis (SD) is a chronic inflammatory skin disease with a multifactorial aetiology. Malassezia yeasts have been associated with the disease but the role of bacterial composition in SD has not been thoroughly investigated.

Objectives

To profile the bacterial microbiome of SD patients and compare this with the microbiome of individuals with no inflammatory skin disease (controls).

Methods

This was a cross sectional study embedded in a population-based study. Skin swabs were taken from naso-labial fold from patients with seborrheic dermatitis (lesional skin: n = 22; non-lesional skin SD: n = 75) and controls (n = 465). Sample collection began in 2016 at the research facility and is still ongoing. Shannon and Chao1 α- diversity metrics were calcu

SUBMITTER: Sanders MGH 

PROVIDER: S-EPMC8143393 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature