Entamoeba gingivalis: epidemiology, genetic diversity and association with oral microbiota signatures in North Eastern Tanzania.

ABSTRACT:

Background

Entamoeba gingivalis has been associated with periodontal diseases. Baseline data from the background population, which could help delimit the role of the parasite in health and disease, remain limited.

Objective

To describe epidemiological features, genetic diversity, and associations with oral microbiome signatures of E. gingivalis colonisation in Tanzanians with non-oral/non-dental diseases.

Methods

DNAs from 92 oral washings from 52 participants were subject to metabarcoding of ribosomal genes. DNA sequences were identified to genus level and submitted to oral microbiota diversity analyses.

Results

Sixteen (31%) of the 52 study participants were E. gingivalis-positive, with no difference in positivity rate according to gender

SUBMITTER: Stensvold CR 

PROVIDER: S-EPMC8143617 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature