Muscular HSP70 content is higher in elderly compared to young, but is normalized after 12 weeks of strength training.

ABSTRACT:

Purpose

Aging is associated with increased myocellular stress and loss of muscle mass and function. Heat shock proteins (HSPs) are upregulated during periods of stress as part of the cells protective system. Exercise can affect both acute HSP regulation and when repeated regularly counteract unhealthy age-related changes in the muscle. Few studies have investigated effects of exercise on HSP content in elderly. The aim of the study was to compare muscular HSP levels in young and elderly and to investigate how training affects HSP content in muscles from aged males and females.

Methods

Thirty-eight elderly were randomized to 12 weeks of strength training (STG), functional strength training (FTG) or a control group (C). To compare elderly to young, 13 untrained young performed

SUBMITTER: Cumming KT 

PROVIDER: S-EPMC8144120 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature