Rapid controlled release by photo-irradiation using morphological changes in micelles formed by amphiphilic lophine dimers.

ABSTRACT: Photo-induced rapid control of molecular assemblies, such as micelles and vesicles, enables effective and on-demand release of drugs or active components, with applications such as drug delivery systems (DDS) and cosmetics. Thus far, no attempts to optimize the responsiveness of photoresponsive molecular assemblies have been published. We previously reported photoresponsive surfactants bearing a lophine dimer moiety that exhibit fast photochromism in confined spaces, such as inside a molecular assembly. However, rapid control of the micelle structures and solubilization capacity have not yet been demonstrated. In the present work, photo-induced morphological changes in micelles were monitored using in-situ small-angle neutron scattering (SANS) and UV/Vis absorption spectroscopy. An amphiph

SUBMITTER: Akamatsu M 

PROVIDER: S-EPMC8144387 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature