Effects of Saffron Extract on Sleep Quality: A Randomized Double-Blind Controlled Clinical Trial.

ABSTRACT: A saffron extract has been found to be effective in the context of depression and anxiety, but its effect on sleep quality has not been investigating yet using objective approaches. For this purpose, a randomized double-blind controlled study was conducted in subjects presenting mild to moderate sleep disorder associated with anxiety. Sixty-six subjects were randomized and supplemented with a placebo (maltodextrin) or a saffron extract (15.5 mg per day) for 6 weeks. Actigraphy was used to collect objective data related to sleep quality at baseline, at the middle and at the end of the intervention. Sleep quality was also assessed by completion of the LSEQ and PSQI questionnaires and quality of life by completion of the SF-36 questionnaire. Six weeks of saffron supplementation led to an incr

SUBMITTER: Pachikian BD 

PROVIDER: S-EPMC8145009 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature