Soft Sensor Development for Real-Time Process Monitoring of Multidimensional Fractionation in Tubular Centrifuges.

ABSTRACT: High centrifugal acceleration and throughput rates of tubular centrifuges enable the solid-liquid size separation and fractionation of nanoparticles on a bench scale. Nowadays, advantageous product properties are defined by precise specifications regarding particle size and material composition. Hence, there is a demand for innovative and efficient downstream processing of complex particle suspensions. With this type of centrifuge working in a semi-continuous mode, an online observation of the separation quality is needed for optimization purposes. To analyze the composition of fines downstream of the centrifuge, a UV/vis soft sensor is developed to monitor the sorting of polymer and metal oxide nanoparticles by their size and density. By spectroscopic multi-component analysis, a measured

SUBMITTER: Winkler M 

PROVIDER: S-EPMC8145064 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature