Genomic Characterization of Salmonella typhimurium DT104 Strains Associated with Cattle and Beef Products.

ABSTRACT: Salmonella enterica subsp. enterica serovar Typhimurium DT104, a multidrug-resistant phage type, has emerged globally as a major cause of foodborne outbreaks particularly associated with contaminated beef products. In this study, we sequenced three S. Typhimurium DT104 strains associated with a 2009 outbreak caused by ground beef, including the outbreak source strain and two clinical strains. The goal of the study was to gain a stronger understanding of the genomics and genomic epidemiology of highly clonal S. typhimurium DT104 strains associated with bovine sources. Our study found no single nucleotide polymorphisms (SNPs) between the ground beef source strain and the clinical isolates from the 2009 outbreak. SNP analysis including twelve other S. typhimuriu

SUBMITTER: Parker CT 

PROVIDER: S-EPMC8145149 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature