Choosing an appropriate glomerular filtration rate estimating equation: role of body mass index.

ABSTRACT:

Background

We aimed to investigate the accuracy of different equations in evaluating estimated glomerular filtration rate (eGFR) in a Chinese population with different BMI levels.

Methods

A total of 837 Chinese patients were enrolled, and the eGFRs were calculated by three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations, three full-age spectrum (FAS) equations and two Modification of Diet in Renal Disease (MDRD) equations. Results of measured GFR (mGFR) by the 99Tcm-diathylenetriamine pentaacetic acid (99Tcm-DTPA) renal dynamic imaging method were the reference standards. According to BMI distribution, the patients were divided into three intervals: below 25th(BMI_P25), 25th to 75th(BMI_P25-75) and over 75th percentiles (BMI_P75<

SUBMITTER: Li J 

PROVIDER: S-EPMC8145837 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature