Genome-wide DNA mutations in Arabidopsis plants after multigenerational exposure to high temperatures.

ABSTRACT:

Background

Elevated temperatures can cause physiological, biochemical, and molecular responses in plants that can greatly affect their growth and development. Mutations are the most fundamental force driving biological evolution. However, how long-term elevations in temperature influence the accumulation of mutations in plants remains unknown.

Results

Multigenerational exposure of Arabidopsis MA (mutation accumulation) lines and MA populations to extreme heat and moderate warming results in significantly increased mutation rates in single-nucleotide variants (SNVs) and small indels. We observe distinctive mutational spectra under extreme and moderately elevated temperatures, with significant increases in transition and transversion frequencies. Mutation occurs more frequentl

SUBMITTER: Lu Z 

PROVIDER: S-EPMC8145854 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature