Unknown

Dataset Information

0

Dandelion flower-like micelles.


ABSTRACT: Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s-1. Similar to the property of dandelion flowers dispersing their seeds over a long distance, the DFMs demonstrated enhanced multicellular tumor spheroid (MTS) penetration, a useful property in the treatment of many diseases including cancer, infection-of-biofilm diseases and ocular problems.

SUBMITTER: Yao Y 

PROVIDER: S-EPMC8146335 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Dandelion flower-like micelles.

Yao Yongchao Y   Xu Deqiu D   Zhu Yuhong Y   Dai Xin X   Yu Yunlong Y   Luo Jianbin J   Zhang Shiyong S  

Chemical science 20191203 3


Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s<sup>-1</sup>. Similar to the property of dandelion flowers dispersing their seeds over a long distance, the DFMs demonstrated enhanced multicellular tumor spheroid (MTS) penetration, a useful property in the treatment of many diseas  ...[more]

Similar Datasets

| S-EPMC6143283 | biostudies-literature
| S-EPMC10739602 | biostudies-literature
| S-EPMC10219969 | biostudies-literature
| S-EPMC11377288 | biostudies-literature
| S-EPMC3244948 | biostudies-other
| S-EPMC1178413 | biostudies-other
| S-EPMC5850771 | biostudies-literature
| S-EPMC6839635 | biostudies-literature
| S-EPMC11266672 | biostudies-literature
| S-EPMC9797189 | biostudies-literature