Ontology highlight
ABSTRACT:
SUBMITTER: Yao Y
PROVIDER: S-EPMC8146335 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Yao Yongchao Y Xu Deqiu D Zhu Yuhong Y Dai Xin X Yu Yunlong Y Luo Jianbin J Zhang Shiyong S
Chemical science 20191203 3
Dandelion flower-like micelles (DFMs) were prepared by self-assembly of polycaprolactone (PCL) functionalized surface cross-linked micelles (SCMs). Upon reductive stimuli, the SCMs can be released from the DFMs by non-Brownian motion at an average speed of 19.09 μm s<sup>-1</sup>. Similar to the property of dandelion flowers dispersing their seeds over a long distance, the DFMs demonstrated enhanced multicellular tumor spheroid (MTS) penetration, a useful property in the treatment of many diseas ...[more]