Lateral Degassing Method for Disposable Film-Chip Microfluidic Devices.

ABSTRACT: It is critical to develop a fast and simple method to remove air bubbles inside microchannels for automated, reliable, and reproducible microfluidic devices. As an active degassing method, this study introduces a lateral degassing method that can be easily implemented in disposable film-chip microfluidic devices. This method uses a disposable film-chip microchannel superstrate and a reusable substrate, which can be assembled and disassembled simply by vacuum pressure. The disposable microchannel superstrate is readily fabricated by bonding a microstructured polydimethylsiloxane replica and a silicone-coated release polymeric thin film. The reusable substrate can be a plate that has no function or is equipped with the ability to actively manipulate and sense substances in the microchannel b

SUBMITTER: Park S 

PROVIDER: S-EPMC8146472 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature