Electron Beam Sterilization of Poly(Methyl Methacrylate)-Physicochemical and Biological Aspects.

ABSTRACT: Electron beam (E-beam) irradiation is an attractive and efficient method for sterilizing clinically implantable medical devices made of natural and/or synthetic materials such as poly(methyl methacrylate) (PMMA). As ionizing irradiation can affect the physicochemical properties of PMMA, understanding the consequences of E-beam sterilization on the intrinsic properties of PMMA is vital for clinical implementation. A detailed assessment of the chemical, optical, mechanical, morphological, and biological properties of medical-grade PMMA after E-beam sterilization at 25 and 50 kiloGray (kGy) is reported. Fourier transform infrared spectroscopy, thermogravimetric analysis, and differential scanning calorimetry studies indicate that E-beam irradiation has minimal effect on the chemical propertie

SUBMITTER: Sharifi S 

PROVIDER: S-EPMC8147572 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature