Ontology highlight
ABSTRACT:
SUBMITTER: Yechezkel I
PROVIDER: S-EPMC8147963 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Yechezkel Itai I Law Mansun M Tzarum Netanel N
Viruses 20210504 5
Hepatitis C virus (HCV) is a serious and growing public health problem despite recent developments of antiviral therapeutics. To achieve global elimination of HCV, an effective cross-genotype vaccine is needed. The failure of previous vaccination trials to elicit an effective cross-reactive immune response demands better vaccine antigens to induce a potent cross-neutralizing response to improve vaccine efficacy. HCV E1 and E2 envelope (Env) glycoproteins are the main targets for neutralizing ant ...[more]