Ontology highlight
ABSTRACT:
SUBMITTER: Dabbagh D
PROVIDER: S-EPMC8147968 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Dabbagh Deemah D He Sijia S Hetrick Brian B Chilin Linda L Andalibi Ali A Wu Yuntao Y
Viruses 20210504 5
Mucins and mucin-like molecules are highly glycosylated, high-molecular-weight cell surface proteins that possess a semi-rigid and highly extended extracellular domain. P-selectin glycoprotein ligand-1 (PSGL-1), a mucin-like glycoprotein, has recently been found to restrict HIV-1 infectivity through virion incorporation that sterically hinders virus particle attachment to target cells. Here, we report the identification of a family of antiviral cellular proteins, named the Surface-Hinged, Rigidl ...[more]