Ontology highlight
ABSTRACT:
SUBMITTER: Bai Y
PROVIDER: S-EPMC8148076 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Bai Yugang Y Xing Hang H Bai Yunhao Y Tan Li Huey LH Hwang Kevin K Li Ji J Lu Yi Y Zimmerman Steven C SC
Chemical science 20200102 6
DNA-nanoparticle conjugates have found widespread use in sensing, imaging, and as components of devices. However, their synthesis remains relatively complicated and empirically based, often requiring specialized protocols for conjugates of different size, valence, and elemental composition. Here we report a novel, bottom-up approach for the synthesis of DNA-nanoparticle conjugates, based on ring-opening metathesis polymerization (ROMP), intramolecular crosslinking, and template synthesis. Using ...[more]