Probiotic-Based Vaccines May Provide Effective Protection against COVID-19 Acute Respiratory Disease.

ABSTRACT: Severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2) infection, the causative agent of COVID-19, now represents the sixth Public Health Emergency of International Concern (PHEIC)-as declared by the World Health Organization (WHO) since 2009. Considering that SARS-CoV-2 is mainly transmitted via the mucosal route, a therapy administered by this same route may represent a desirable approach to fight SARS-CoV-2 infection. It is now widely accepted that genetically modified microorganisms, including probiotics, represent attractive vehicles for oral or nasal mucosal delivery of therapeutic molecules. Previous studies have shown that the mucosal administration of therapeutic molecules is able to induce an immune response mediated by specific serum IgG and mucosal IgA antibodies al

SUBMITTER: Taghinezhad-S S 

PROVIDER: S-EPMC8148110 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature