Modular barcode beads for microfluidic single cell genomics.

ABSTRACT: Barcode beads allow efficient nucleic acid tagging in single cell genomics. Current barcode designs, however, are fabricated with a particular application in mind. Repurposing to novel targets, or altering to add additional targets as information is obtained is possible but the result is suboptimal. Here, we describe a modular framework that simplifies generation of multifunctional beads and allows their easy extension to new targets.

SUBMITTER: Delley CL 

PROVIDER: S-EPMC8149635 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature