Alterations of Serum Metabolites and Fecal Microbiota Involved in Ewe Follicular Cyst.

ABSTRACT: While the interactions of the gut microbiome and blood metabolome have been widely studied in polycystic ovary disease in women, follicular cysts of ewes have been scarcely investigated using these methods. In this study, the fecal microbiome and serum metabolome were used to compare between ewes diagnosed with ovarian cystic follicles and ewes with normal follicles, to investigate alterations of the fecal bacterial community composition and metabolic parameters in relation to follicular cystogenesis. Ewes from the same feeding and management system were diagnosed with a follicular cyst (n = 6) or confirmed to have normal follicles (n = 6) by using a B-mode ultrasound scanner. Blood serum and fresh fecal samples of all ewes were collected and analyzed. The α-diversity of feca

SUBMITTER: Feng T 

PROVIDER: S-EPMC8149755 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature