Influence of Serum Albumin on HbA1c and HbA1c-Defined Glycemic Status: A Retrospective Study.

ABSTRACT: Background: Glycated hemoglobin (HbA1c) is commonly used in the diagnosis and evaluation of glycemic control in diabetes, and it may be influenced by several non-glycemic and glycemic factors, including albumin. This retrospective study investigated the influence of albumin on HbA1c and HbA1c-defined glycemic status. Methods: The demographic, hematological, and biochemical data were collected for 11,922 patients undergoing routine physical examination. Univariate and multivariate linear regression analyses, stratified analyses and interaction analyses, and multiple logistic regression were conducted to identify the association between albumin and HbA1c in people with different glycemic status. Results: HbA1c levels were inversely associated with serum albumin level (

SUBMITTER: Feng X 

PROVIDER: S-EPMC8149759 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature