Benzodiazepine Use and Long-Term Mortality in South Korean Adult Population: A Cohort Study.

ABSTRACT:

Purpose

Studies have reported mixed results on the association between benzodiazepine use and mortality. Here, we investigated whether benzodiazepine use is associated with a higher risk of 5-year all-cause mortality, and examined the association between benzodiazepine use and 5-year disease-specific mortality.

Materials and methods

In this population-based cohort study, a nationally representative sample cohort in South Korea was examined. In 2010, benzodiazepine users were defined as individuals prescribed benzodiazepine continuously over 30 days for regular administration, and all other subjects were included in the control group. The primary endpoint was 5-year all-cause mortality, evaluated from 2011 to 2015. Propensity score (PS) matching and time-dependent Cox regress

SUBMITTER: Oh TK 

PROVIDER: S-EPMC8149930 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature