Gait Impairment and Upper Extremity Disturbance Are Associated With Total Magnetic Resonance Imaging Cerebral Small Vessel Disease Burden.

ABSTRACT: Background and Purpose: Cerebral small vessel disease (cSVD)-including white matter hyperintensities (WMHs), cerebral microbleeds (CMBs), lacunes, and enlarged perivascular spaces (EPVS)-is related to gait impairment. However, the association between the total magnetic resonance imaging (MRI) cSVD burden and gait and upper extremity function remains insufficiently investigated. This study aimed to assess the correlation between the total MRI cSVD burden score and gait impairment as well as upper extremity impairment. Method: A total of 224 participants underwent MRI scans, and the presence of lacunes, WMHs, CMBs, and EPVS was evaluated and recorded as a total MRI cSVD burden score (range 0-4). Gait was assessed by 4-m walkway, Tinetti, Timed Up and Go (TUG), and Short Physica

SUBMITTER: Hou Y 

PROVIDER: S-EPMC8149961 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature