Functional Brain Connectivity Patterns Associated with Visual Hallucinations in Dementia with Lewy Bodies.

ABSTRACT:

Background

The presence of recurrent, complex visual hallucinations (VH) is among the core clinical features of dementia with Lewy bodies (DLB). It has been proposed that VH arise from a disrupted organization of functional brain networks. However, studies are still limited, especially investigating the resting-state functional brain features underpinning VH in patients with dementia.

Objective

The aim of the present pilot study was to investigate whether there were any alterations in functional connectivity associated with VH in DLB.

Methods

Seed-based analyses and independent component analysis (ICA) of resting-state fMRI scans were carried out to explore differences in functional connectivity between DLB patients with and without VH.

Results

Seed-based analy

SUBMITTER: Pezzoli S 

PROVIDER: S-EPMC8150258 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature