Trends of incidence and prognosis of primary adenocarcinoma of the bladder.

ABSTRACT:

Background

Primary adenocarcinoma of the bladder (ACB) is a rare malignant tumor of the bladder with limited understanding of its incidence and prognosis.

Methods

Patients diagnosed with ACB between 2004 and 2015 were obtained from the SEER database. The incidence changes of ACB patients between 1975 and 2016 were detected by Joinpoint software. Nomograms were constructed based on the results of multivariate Cox regression analysis to predict overall survival (OS) and cancer-specific survival (CSS) in patients with ACB, and the constructed nomograms were validated.

Results

The incidence of ACB was trending down from 1991 to 2016. A total of 1039 patients were included in the study and randomly assigned to the training cohort (727) and validation cohort (312). In the t

SUBMITTER: Lu H 

PROVIDER: S-EPMC8150450 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature