Association Between Bitter Taste Receptor Phenotype and Clinical Outcomes Among Patients With COVID-19.

ABSTRACT:

Importance

Bitter taste receptors (T2Rs) have been implicated in sinonasal innate immunity, and genetic variation conferred by allelic variants in T2R genes is associated with variation in upper respiratory tract pathogen susceptibility, symptoms, and outcomes. Bitter taste receptor phenotype appears to be associated with the clinical course and symptom duration of SARS-CoV-2 infection.

Objective

To evaluate the association between T2R phenotype and patient clinical course after infection with SARS-CoV-2.

Design, setting, and participants

A prospective cohort study was performed from July 1 through September 30, 2020, at a tertiary outpatient clinical practice and inpatient hospital in the United States among 1935 participants (patients and health care workers) with o

SUBMITTER: Barham HP 

PROVIDER: S-EPMC8150696 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature