Long-term exposure to ambient PM_2.5 and stroke mortality among urban residents in northern China.

ABSTRACT: Evidence is still limited for the role of long-term PM_2.5 exposure in cerebrovascular diseases among residents in high pollution regions. The study is aimed to investigate the long-term effects of PM_2.5 exposure on stroke mortality, and further explore the effect modification of temperature variation on the PM_2.5-mortality association in northern China. Based on a cohort data with an average follow-up of 9.8 years among 38,435 urban adults, high-resolution estimates of PM_2.5 derived from a satellite-based model were assigned to each participant. A Cox regression model with time-varying exposures and strata of geographic regions was employed to assess the risks of stroke mortality associated with PM_2.5, after adjusting for individual ri

SUBMITTER: Yang X 

PROVIDER: S-EPMC8150861 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature