Predictors of training-related improvement in visuomotor performance in patients with multiple sclerosis: A behavioural and MRI study.

ABSTRACT:

Background

The development of tailored recovery-oriented strategies in multiple sclerosis requires early identification of an individual's potential for functional recovery.

Objective

To identify predictors of visuomotor performance improvements, a proxy of functional recovery, using a predictive statistical model that combines demographic, clinical and magnetic resonance imaging (MRI) data.

Methods

Right-handed multiple sclerosis patients underwent baseline disability assessment and MRI of the brain structure, function and vascular health. They subsequently undertook 4 weeks of right upper limb visuomotor practice. Changes in performance with practice were our outcome measure. We identified predictors of improvement in a training set of patients using lasso re

SUBMITTER: Lipp I 

PROVIDER: S-EPMC8151554 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature